Open access
Oct 2026
Oleanolic Acid-Loaded Cyclodextrin Metal–Organic Framework Ameliorates NAFLD via Modulation of Gut Microbiota and Liver Metabolism
Oleanolic acid (OA) possesses hepatoprotective properties, but its clinical application is hampered by poor aqueous solubility. This study aimed to enhance OA solubility and investigate its therapeutic mechanism for NAFLD by encapsulating it in a γ-cyclodextrin metal–organic framework (OA@CDMOF). The OA@CDMOF complex w...
Hua Zhu, Min-Min Tang, Meng Li et al.
· Molecules · 0 citations