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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Zhenlei Zhang

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Open access Sep 2026

HDAC1 maintains metabolic homeostasis in nucleus pulposus cells via post-translational modification interactions with YBX1

Intervertebral disc degeneration is characterized by the metabolic dysregulation of nucleus pulposus cells, which is regulated by complex post-translational modifications, manifesting as extracellular matrix remodeling and inflammatory microenvironment formation. We demonstrated the progressive downregulation of HDAC1...

Bo Zhou, Jie-Yun Xia, Zhao-Wei Zhang et al. · 0 citations
Aug 2026

Bimetallic modified titanium carbide nanoparticles loaded with transcription factor E3 ameliorate intervertebral disc degeneration by eliminating reactive oxygen species and promoting autophagic flux.

In a needle puncture-induced IVDD rat model, intra-disc injection of Ti3C2@PtAu@TFE3 alleviated structural deterioration and prevented ECM destruction and the potential application of Ti3C2@PtAu@TFE3 against IVDD is demonstrated.

Jianle Wang, Tian-You Gao, Yingfeng Su et al. · 0 citations

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