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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Zhen Li

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Open access Aug 2026

Development and validation of a two-gene urine DNA methylation assay for noninvasive prostate cancer detection: a prospective multicenter study

Prostate-specific antigen (PSA) screening lacks specificity, particularly within the 4–10 ng/mL diagnostic gray zone, leading to unnecessary prostate biopsies and overtreatment. Here, we developed and validated a streamlined urine DNA methylation assay for non-invasive prostate cancer (PCa) detection and biopsy decisio...

Dingwen Liu, Lian Tang, Wei Xiong et al. · 0 citations

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