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Author

Zhen-Ning Wang

2 papers indexed here

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Review Oct 2026

Neoadjuvant short-course radiotherapy followed by camrelizumab and chemotherapy versus standard of care for locally advanced rectal cancer (UNION): a prespecified interim analysis of a multicentre, open-label, randomised, phase 3 trial.

BACKGROUND To our knowledge, UNION is the first phase 3 trial to assess a neoadjuvant strategy incorporating radiotherapy, immunotherapy, and chemotherapy compared with standard care in patients with locally advanced rectal cancer, which reported positive results for the primary endpoint (blinded independent review com...

Kai-Xiong Tao, Zhen-Yu Lin, Peng Zhang et al. · 0 citations
Open access Oct 2026

CDK9 Degradation Suppresses Gastroesophageal Cancer Growth and Overcomes Radiation Resistance through Chromatin Remodeling and YAP1/TEAD Downregulation.

Gastroesophageal adenocarcinoma (GEAC) remains a highly aggressive malignancy with limited effective targeted therapies. Cyclin-dependent kinase 9 (CDK9), a key regulator of transcriptional elongation, has been implicated in oncogenic processes across multiple cancer types; however, its functional role and therapeutic...

Y. Zhang, Mikel Ghelfi, Yu Xue et al. · 0 citations

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