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Open access Aug 2026

Chronic kidney disease promotes anxiety susceptibility through an angiotensin II–central amygdala axis

Background Neuropsychiatric comorbidities are highly prevalent in chronic kidney disease (CKD), yet the underlying neural mechanisms remain poorly defined. Methods We established multiple mouse models of CKD and identified an adenine-induced model as the most suitable platform to study neurobehavioral alterations. Anxi...

Yuting Liu, Yu-Jian He, Xinzhou Zhang et al. · 0 citations

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