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Author

Zhen Wang

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Nov 2026

Characterization of Pulmonary Tropism, Expression Kinetics and Safety of the Novel Adeno-Associated Virus-LungM3 Vector.

This study investigated the lung-targeting characteristics, dose- and time-dependent effects, and safety of a novel engineered adeno-associated virus (AAV) vector, AAV-LungM3. In vitro, mouse primary lung organoids were transduced with AAV-LungM3 at doses of 103, 104, and 105 vector genomes (vg)/cell, and transduction...

Heng-Hai Nie, Juan Du, Xi-Feng Feng et al. · 0 citations
Review Open access Sep 2026

Tissue‐Resident Macrophage in Inflammation and Cancer

Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological dysfunction. This review provides a comprehensive analysis of TRM biology in inflammation and cancer. We first delineate the het...

Si-Yuan Huang, Jiang-Bo Fan, Wen-Yi Liu et al. · 0 citations
Aug 2026

Methylsulfonylmethane protects against lethal MRSA infection via binding to PIK3CB to increase macrophage phagocytic function and nitric oxide production.

MSM alleviates lethal MRSA infection by enhancing macrophage phagocytosis and promoting NO production to eliminate intracellular bacteria, position MSM as a promising therapeutic agent against drug-resistant bacterial infections, offering a novel strategy for managing sepsis.

Hao-Ru Liu, Wan-Qi Tang, Hongsheng Zheng et al. · 0 citations

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