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Zhen-Xiao Ren

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Open access Oct 2026

Cardiometabolic vulnerability and incident frailty across three aging cohorts: a multicohort longitudinal study of HRS, ELSA, and CHARLS

Cardiometabolic dysfunction is linked to frailty, but whether a fixed-weight biomarker score developed for one functional aging outcome retains an association with incident frailty without re-estimating its weights is unknown. We evaluated the systolic blood pressure–HDL–A1c–CRP (SHAC) index, originally developed...

Zhao-Bei Cai, Zhen-Xiao Ren · 0 citations

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