Zhen-Xin Shen

Low-duty-cycle pulsed ultrasound for ex vivo liver tissue ablation: thermal safety, lesion conformity, and vascular structure preservation.

OBJECTIVE To investigate the physical mechanisms and engineering efficacy of low-duty-cycle pulsed ultrasound (histotripsy) in overcoming the heat sink effect and preserving major hepatic vessels.Impact Statement: This study provides a highly conformal, non-thermal ablation strategy that eliminates blood flow cooling e...