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Zhen-Yu Xi

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Open access Oct 2026

Aziridination-Based Crosslinking Enables Site-Resolved Elucidation of Lipid Binding and Protein Conformational Changes

Lipid–protein interactions play critical roles in cellular function, yet their site-resolved characterization remains challenging due to the dynamic nature of lipid binding and the limited availability of chemoselective strategies for covalently capturing native lipid–protein contacts. Here, we introduce aziridinatio...

Chia-Lung Tsai, A. Tasnim, Zhen-Yu Xi et al. · 0 citations
Open access Aug 2026

Dynamics of the Myoglobin/Heme Complex: A Limited Proteolysis Perspective

The dynamics and stabilities (i.e., physicochemical properties) of proteins and protein complexes are dictated by the solution environment. Changes in the solution environment may alter the distribution of states present in solution (i.e., the free-energy landscape) and thus their physicochemical properties. This wor...

Carter Lantz, Leila Minian, Roza Avetisyan et al. · 0 citations

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