Open access
Aug 2026
Integrated multi-omics, network pharmacology, and experimental validation reveal the protective mechanisms of curcumol against DSS-induced ulcerative colitis
Background Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease characterized by mucosal immune imbalance, epithelial barrier disruption, and intestinal dysbiosis. Curcumol (CUR) possesses anti-inflammatory and immunomodulatory activities; however, the multilevel mechanisms underlying its protectiv...
Fu Shu, Kai-Qi Chen, Ying-Jie Song et al.
· Frontiers in Immunology · 0 citations