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Author

Zheng Chen

2 papers indexed here

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Open access Aug 2026

Identification of novel linear antigenic epitope of IBDV VP3 recognized by monoclonal antibodies

This study aims to prepare specific monoclonal antibodies (mAbs) of IBDV VP3. We purified the recombinant VP3 protein to immunize the BALB/c mice for subsequently cell fusion. Following three rounds of sub-cloning, we successfully obtained three hybridoma cell lines (3B, 5 G, 6A) capable of stably secreting anti-VP3 mA...

Cheng-Yu He, Zhi-Xuan Xiong, Hui-Ping Liang et al. · 0 citations
Aug 2026

MARK1 suppresses infectious bursal disease virus replication via phosphorylating VP3.

Infectious bursal disease virus (IBDV) of the Birnaviridae family is a non-envelope, double-stranded RNA virus that encodes a VP3 protein with multiple functions, which controls viral genome replication, IFN-β production, and virus traffic in infected cells. Posttranslational modifications (PTMs), such as ubiquitinatio...

Cheng-Yu He, Xifeng Hu, Hui-Ping Liang et al. · 0 citations

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