Author

Zheng-Hao Lin

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Oct 2026

GraphSC: Deep Graph Learning With Spectral Clustering for Flexible Gene Co-Expression Module Detection Across Pan-Cancer.

Identifying gene co-expression (GCE) modules from transcriptomic data is critical for understanding cellular functions and disease mechanisms. Traditional methods often rely on rigid assumptions to detect modules with specific topologies (e.g., spherical clusters or fully connected cliques), limiting their ability to c...

Zi-Xiao Lu, Shu-Ting Yang, Yi-Lin Chen et al. · IEEE journal of biomedical a... · 0 citations

Open access Sep 2026

BOMIFA: biologically informed multi-omics integration with graph contrastive learning for cancer prognosis in women

A biologically informed cross-omics attention mechanism is deployed to explicitly model directional regulatory dependencies, enabling inter-omics information exchange aligned with known molecular hierarchies and enabling the identification of female-associated prognostic biomarkers that were overlooked in prior mixed-s...

Zi-Xiao Lu, Jia-Jun Wang, Yu-Ping Liang et al. · Briefings in Bioinformatics · 0 citations