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Aug 2026

Caged Glycan-Antibody Conjugates for Tumor-Selective Activation of Lysosome-Targeting Chimeras.

A chemically activatable LYTAC platform that leverages tumor microenvironment-specific cues to achieve precise and safe protein degradation in vivo is reported, significantly enhancing the safety and therapeutic window of lysosome-targeted degradation strategies in cancer therapy.

Mohan Chen, Yi-Cun Li, Xue-Ting Wei et al. · 0 citations

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