A novel chimeric antimicrobial peptide B5PL dual-targets bacterial cell membrane and neutrophils to combat multidrug-resistant bacterial infections.
Methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Klebsiella pneumoniae (MDR-KP) pose severe threats to global public health due to lack of effective therapeutic strategies. Conventional antibacterial agents exhibit limited potency for modulating host immune defense responses. This study design...