Dyshomeostasis of the autonomic nervous system (ANS) drives chronic illnesses including hypertension, heart failure, diabetes mellitus, metabolic syndrome, Parkinson's disease, and traumatic brain injury. Abnormal neuronal excitability within central nervous system (CNS) nuclei is a major cause of ANS dysfunction. Smal...
Ren-Jun Wang, Zheng-Wei Li, Andrew D. Chapp et al.· Neuroscience Bulletin· 0 citations
Excessive sympathetic overactivation serves as a core pathological mechanism underlying the initiation and progression of cardiovascular diseases such as hypertension. The hypothalamic paraventricular nucleus (PVN) acts as a pivotal integrative nucleus of the sympathetic center, and functional imbalance of neuronal ion...
Bo Xu, Bai-Tong Liu, Yu Zhao et al.· Neuroscience· 0 citations
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