Zheng Yang

A programmable spatiotemporal bioelectrical conduit promotes peripheral nerve regeneration by suppressing ferroptosis through modulation of ER–mitochondria coupling in Schwann cells

Following peripheral nerve injury, abnormal endoplasmic reticulum–mitochondria coupling and activation of ferroptosis in Schwann cells are important causes of impaired myelination and regenerative failure. Based on this, we developed a multiscale anisotropic electroactive nerve conduit. The outer layer consists of a Ba...