Structural-Guided Latent Diffusion for MRI-to-PET Synthesis and Alzheimer’s Disease Diagnosis
Multimodal neuroimaging is crucial for Alzheimer’s disease (AD) diagnosis, yet positron emission tomography (PET) is often unavailable due to its cost and limited accessibility. We propose a structural-guided latent diffusion framework for synthesizing PET from structural MRI while jointly learning disease-discriminati...