Jul 2026
METTL3–YTHDF1–driven m6A enhancement of MYC signaling orchestrates DNA repair and metabolic reprogramming to promote chemoresistance in colorectal cancer
It is revealed that m6A-regulated MYC signaling orchestrates DNA repair and metabolic remodeling to promote CRC chemoresistance and highlights the METTL3–YTHDF1–MYC axis as a promising target for predictive precision therapy and combined therapeutic interventions.
Kai Wang, Song Geng, Zhengping Xiao et al.
· Molecular and Cellular Bioch... · 0 citations