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Author

Zhengqiu Li

2 papers indexed here

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Open access Oct 2026

Affinity-Based Proteome Profiling to Identify Targets of Tuberculosis Antibiotics

Drug-resistant Mycobacterium tuberculosis is an increasing global health crisis that requires the urgent development of new antibiotics. Understanding the mechanism of action of new inhibitors is an essential but challenging component of drug discovery. Affinity-based proteome profiling (AfBP) is a powerful approach...

Li-Yan Huang, Kang Duan, C. Adolph et al. · 0 citations
Open access Aug 2026

A New Recruitable E3 Ligase UHRF1 Supporting Targeted Protein Degradation: A Minimal Azide as a Recruitment Ligand

The first small-molecule GPX4 degraders that incorporate either electrophilic warheads or a minimal azide group as an E3 recruitment ligand are reported, thereby expanding the E3 ligase toolbox and offering a promising strategy for targeted cancer therapy.

Ze-Hong Lin, Kang Duan, Rui Wan et al. · 0 citations

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