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Zhengshuang Li

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Jul 2026

Pathogenicity and Genomic Analysis of Hypervirulent Aeromonas hydrophila NN0116 From Nile Tilapia and Head Kidney Transcriptome of Infected Fish Reveals a B-Cell-Dominated Immune Response.

Aeromonas hydrophila is a major pathogen of Motile Aeromonad Septicemia (MAS) in Nile tilapia, with pathogenesis and immunity poorly understood. In early 2026, a > 70% mortality outbreak occurred at a Nanning tilapia farm. The dominant strain NN0116 was identified as A. hydrophila by 16S rRNA and whole-genome ANI analy...

Fuhao Geng, Jifeng Zhang, Zulin Fang et al. · 0 citations
Aug 2026

Genomic characterization of a hypervirulent Aeromonas veronii NN0115 from Nile tilapia and head kidney transcriptome of infected fish reveals B-cell-dominated immune response with specific immunoglobulin downregulation.

This study provides a comprehensive characterization of a highly virulent A. veronii from Nile tilapia and reveals that selective downregulation of B-cell Ig genes is the dominant transcriptional feature of the host head kidney response.

Zulin Fang, Zhengshuang Li, Fuhao Geng et al. · 0 citations

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