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Author

Zhen-Xing Mao

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Aug 2026

Early-Life Exposure to Organophosphorus Pesticide Mixtures and Impaired Neonatal Neurodevelopment: A Cohort Study Integrating Comprehensive Multi-Omics and Machine Learning.

It is suggested that early-life exposure to OPP mixtures is linked to impaired neonatal neurodevelopment, potentially linked to gut microbiota dysregulation and predicted functional alterations, and microbial functional signatures may have potential as early-life predictive markers for later motor deficits.

M. Deng, Jun Qiu, Shi-Ting Xiang et al. · 0 citations
Jul 2026

Association of PM2.5 and its components with cognitive dysfunction among rural older adults: Epidemiological evidence with hypothesis-generating network toxicology analysis.

Long-term exposure to PM2.5 and its components is associated with higher odds of CD in rural older adults, and Ribosomal and mitochondrial pathways may be dysregulated in PM2.5-related neurotoxicity, but candidate genes require further validation.

Huan-Xiang Zhang, Zi-Yuan Zhang, Z. Tian et al. · 0 citations
Aug 2026

Organophosphate flame retardants and incident type 2 diabetes: Integrating population evidence, mechanistic insights, and effect modification by healthy lifestyle.

Mixed OPFRs exposure, dominated by TPHP, was associated with higher incident T2DM risk, partly attenuated by healthier lifestyle trajectories, supporting combined exposure-reduction and lifestyle-based prevention strategies.

Xueyan Wu, Yilin Zhou, Yue Nie et al. · 0 citations

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