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Zhi Chai

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Open access Aug 2026

Mechanism analysis of MPTP-induced Parkinson's disease-like pathology via the HPA axis-microglial glucocorticoid receptor pathway.

MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a neurotoxicant widely used to model Parkinson's disease (PD). However, the mechanisms by which MPTP induces neuroinflammation and dopaminergic (DA) degeneration via the hypothalamic-pituitary-adrenal (HPA) axis remain incompletely understood. In this study, we est...

Lei Xu, Kai-Nan Xiao, Jin-Xu Jiang et al. · 0 citations

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