Eugenol attenuates ferroptosis, mitochondrial damage, and inflammation in cardiac hypertrophy via the 14-3-3γ/AMPKα2 pathway.
BACKGROUND Chronic stress-induced cardiac hypertrophy is often accompanied by energy metabolism within the mitochondria, iron homeostasis, and inflammation. Eugenol (Eug), as an antioxidant, scavenges reactive oxygen species (ROS) in the body and stabilizes the internal cellular environment. However, the mechanism of t...