Connective tissue disease (CTD), being an incurable lifelong condition, is significantly correlated with patients’ psychological well-being during prolonged treatment. This study aims to offer insights into improving mental health by examining the relationship between dyadic coping and psychological resilience in p...
Xing-Feng Cai, Shu-Ai Xu, Xiu-Li Zhong et al.· Frontiers in Psychology· 0 citations
Regulatory T cells (Tregs) help maintain immune balance in hematopoietic niches by interacting with the bone marrow microenvironment. Under normal conditions, surrounding cells send signals that affect Treg movement, their length of stay in the bone marrow, their number and activity. In turn, Tregs affect hematopoietic...
Jia Hua Cheng, Qian Wang, Zhi-Feng Gu et al.· Frontiers in Cell and Develo...· 0 citations
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation within joints, where macrophage-driven inflammatory cascade caused by mitochondrial dysfunction significantly contributes to the pathogenesis. Through recruitment and activation of neutrophils from circulation, these macrop...
Qing-Shui Wen, Yi Jin, Ying Zhou et al.· Advanced Healthcare Material...· 0 citations
This review focuses on the cellular and molecular components, functional roles, pathological alterations, and mechanisms of the BMM in AIDs, and aims to provide an essential foundation for further investigation into the pathogenesis of autoimmune diseases.
Qian Wang, Jia Hua Cheng, Zhi-Feng Gu et al.· Frontiers in Immunology· 0 citations
Increased JOSD2 attenuates the aggressive behaviors of RA-FLS and alleviates synovial inflammation, and the JOSD2-ZNF148 axis may represent a potential therapeutic strategy for RA.
Teng Wu, Qingshui Wen, Yu-Nan Wang et al.· International Immunopharmaco...· 0 citations
This is the first study to demonstrate that Cal exerts anti-TNBC activity through a novel OTUD6B/GPX4-dependent ferroptosis regulatory axis and highlights that Cal warrants further investigation as a potential candidate, and the OTUD6B/GPX4 signaling pathway may represent a significant target for TNBC treatment.
Xue Mao, Yin Lin, Zhifeng Gu et al.· Biochemical and Biophysical...· 0 citations
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