Open access
Sep 2026
Trimethylamine N-oxide promotes lymphoid differentiation of hematopoietic stem and progenitor cells.
BACKGROUND Persistent lymphopenia represents a clinically relevant adverse effect associated with radiotherapy, surgery and infection and is linked to unfavorable clinical outcomes. Trimethylamine N-oxide (TMAO), a gut microbiota-derived metabolite generated from dietary choline and L-carnitine, has emerged as a potent...
Min Zhang, Han-Yi Mei, Xin-Yu Bai et al.
· Molecular Immunology · 0 citations