IFIT1+ Tumor-Associated Macrophages Suppress Cancer Stemness and Enhance Chemosensitivity via the TNFSF10-TNFRSF10B Axis in Epithelial Ovarian Cancer.
BACKGROUND Epithelial ovarian cancer (EOC) is typically diagnosed at an advanced stage and is associated with high mortality due to metastasis and chemoresistance. Cancer stem cells (CSCs) are central to EOC progression, recurrence, and treatment resistance, with their functional behavior shaped by the tumor immune mic...