Author

Zhi-Hong Liu

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Open access Oct 2026

The aMAP Score Effectively Stratifies Hepatocellular Carcinoma Risk in the Steatotic Liver Disease Population

Steatotic liver disease (SLD) is an increasingly important cause of hepatocellular carcinoma (HCC), yet validated risk stratification tools remain limited. We aim to evaluate the aMAP score, initially developed for HCC risk prediction mainly in viral hepatitis across international cohorts, in the SLD population.

Wen-Xin Xu, Ya-Ru Shi, Zhi-Hong Liu et al. · Liver international (Print) · 0 citations

Oct 2026

Toll-like Receptor 7 and Interferon-α Synergy Establishes a Positive Feedback Loop to Potentiate Antiviral Immunity in Chronic Hepatitis B.

BACKGROUND AND OBJECTIVES Current therapies for chronic hepatitis B (CHB) rarely achieve functional cure, underscoring the need for novel immunotherapies. Toll-like receptor 7 (TLR7), a key innate immune sensor, has emerged as a major drug development focus. This study aims to characterize stage-specific TLR7 expressio...

J. Ge, Zi-Xu Chen, Xuan Huang et al. · Antiviral Research · 0 citations