Aug 2026
MRPL35 Suppresses Autophagy-Mediated Ferroptosis in Hepatocellular Carcinoma via the AMPK/mTOR Axis.
A novel regulatory mode of autophagy-reliant ferroptosis was established by the MRPL35/AMPK/mTOR axis in HCC, and the newly characterized MRPL35- AMPK/mTOR axis not only proposes MRPL35 as a therapeutic target for HCC but also advances the understanding of its carcinogenic mechanisms.
Yu-Liang Xu, Li-Shuai Xiao, Zhi-Hu Shi et al.
· Current Cancer Drug Targets · 0 citations