Author

Zhi-Jian Yang

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Open access Dec 2025

Developing Topics.

BACKGROUND Demonstrating the specificity of plasma biomarkers to AD-related neurodegeneration would add support to their prognostic and diagnostic clinical use. METHOD Participants from the Baltimore Longitudinal Study of Aging were cognitively unimpaired at the time of their plasma Aβ42/Aβ40, GFAP, NfL (Quanterix Ne...

Murat Bilgel, Ishaan Shah, Jasmine M. Cooper et al. · Alzheimer's & Dementia · 0 citations

Open access Sep 2026

Association of plasma biomarkers with longitudinal change in age- and Alzheimer’s disease-related brain atrophy patterns

Among CU individuals, plasma p-tau217 was associated with subsequent MCI/dementia due to AD and showed the most extensive associations with longitudinal AD-related brain atrophy, compared with SPARE-BA or R-indices capturing subcortical, diffuse cortical, or perisylvian atrophy.

Murat Bilgel, Ishaan Shah, Jasmine M. Cooper et al. · medRxiv · 0 citations