Zhi-Jie Zeng

Neutrophil extracellular traps promote liver metastasis by impairing NK cell-dependent tumor surveillance via CCDC25

Tumor metastasis requires constant crosstalk between primary tumor cells and immune cells in distant organs, yet how this interaction shapes the evolving immune landscape of metastatic sites remains unclear. Here, using longitudinal single-cell RNA sequencing in a 4T1 orthotopic breast cancer model, we observe a progre...