Zhi-Li Guo

Mechanisms and targeted intervention strategies of macrophage mitochondrial quality control imbalance in the progression of atherosclerosis

Atherosclerosis (AS) is a vascular disease characterized by lipid accumulation, chronic inflammation, and plaque instability, which can lead to severe cardiovascular events, such as myocardial infarction and stroke. Macrophages are the predominant immune cells within plaques and form foam cells upon uptake of oxidized...