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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Zhi-Li Yang

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Open access Sep 2026

Analysis of the plasmid-based ts-mutant Δpa0947 (pTS-pa0947) reveals pa0947 essentiality and dnaA-centered suppressor bypass in Pseudomonas aeruginosa

ABSTRACT PA0947 is annotated as an essential hypothetical protein in Pseudomonas aeruginosa and shares substantial sequence identity with the Escherichia coli replication regulator Hda, yet its cellular function and genetic bypass logic in P. aeruginosa have not been experimentally characterized. Here, we constructed a...

Qing-Hai Tang, Hui-Ting Zhu, Zhi-Li Yang · 0 citations

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