Author

Zhi-Liang Bai

2 papers indexed here

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Open access Sep 2026

Spatial Proteomics and Epigenomics Reveal Cell Morphology and Epigenetic Gene Regulation in Human Hippocampus

Abstract We present the first spatial tri-omic (proteomic, transcriptomic, and epigenomic) taxonomy of human hippocampus, addressing two key challenges in single-cell and spatial transcriptomics: visualizing cell morphology and epigenetic gene regulation in situ. By designing and multiplex imaging a novel panel of 25 p...

Rong Fan, Yang Xiao, Graham Su et al. · Research Square · 0 citations

Open access Aug 2026

All-optical multimodal mapping of single-cell-type-specific metabolic activities via REDCAT

Metabolism is fundamental to cell function, yet its activities vary across tissue environments. Resolving these processes in situ at single-cell resolution is crucial for understanding physiology in health and disease. However, existing methods lack biochemical specificity or direct linkage to cell identity. Here we re...

Ya-Juan Li, Zhao-Jun Zhang, Archibald Enninful et al. · Nature Methods · 0 citations