Author

Zhilin Zhu

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Open access Aug 2026

M2-PRNet: multi-scale and multi-modal learning for protein–RNA binding affinity prediction

The results demonstrate the effectiveness of integrating multi-scale and multi-modal representations with cross-scale alignment for protein–RNA affinity prediction, and suggest that M2-PRNet can highlight relevant RNA-binding regions and support preliminary discrimination between strong and weak binders when plausible complex structures are available.

Junkai Wang, G. Luo, Yun-Song Yang et al. · Bioinformatics · 0 citations

Open access Aug 2026

AbAgKer: a unified semi-supervised framework for antigen-antibody binding affinity and kinetics prediction

This work designs a biological prior-guided feature fusion framework that integrates pseudo-structural epitope knowledge and CDR-specific attention mechanisms via a mixture-of-experts architecture to effectively capture complex binding landscapes in antibody screening and drug residence time analysis.

G. Luo, Junkai Wang, Sizhe Zhang et al. · Bioinformatics · 0 citations