Author

Zhiming Rao

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Sep 2026

A Sequence-to-Scaffold Platform Enables Programmable Carrier-Supported Biocatalysis for Nucleoside Analog Synthesis

Industrial biocatalysis increasingly requires strategies that convert enzyme discovery into robust catalyst systems for process implementation. Here, we report Spatially Programmable Assembly of Computationally Mined Enzymes (SPACE), a sequence-to-scaffold workflow coupling multiparametric enzyme mining with programm...

Qiang Wang, Teng Bao, Jia-He Qiu et al. · ACS Catalysis · 0 citations

Open access Aug 2026

Enhanced Trehalose Production Through Integrated Chassis and Expression Engineering in Bacillus subtilis

Trehalose is a functional disaccharide widely used in the food, pharmaceutical, and cosmetic industries. It is industrially produced via a dual-enzyme process involving maltoligosaccharide trehalose synthase (MTSase) and maltoligosaccharide trehalose hydrolase (MTHase), with Escherichia coli (E. coli) serving as the ex...

Jianghua Chen, Yu-Jue Wang, Qiang Wang et al. · Fermentation · 0 citations