Dopamine-Functionalized Osteon-Mimetic Polycaprolactone/β-Tricalcium phosphate Membranes: Antibacterial Efficacy and MAPK/p53-Mediated Osteohomeostasis
In vivo evaluations in a rat calvarial defect model demonstrated that 24DOPA@M-PCL/β-TCP facilitated superior bone regeneration, characterized by elevated osteocalcin/osteopontin expression and reduced TRAP-positive osteoclast recruitment, underscore the significant clinical translational potential of this biomimetic,...