Construction of in vitro–in vivo correlation (IVIVC) degradation evaluation model of absorbable PCL/β-TCP alveolar bone repair scaffold and exploration of a biosafety evaluation idea based on “homeostasis”
Abstract Traditional in vivo degradation assessments for resorbable medical devices face challenges due to extreme durations, high costs and a lack of criteria for reaching tissue-response steady states. This study investigates a 3D-printed PCL/β-TCP bone grafting scaffold by designing a model that correlates multi-sta...