Zhi-Wei Qi

Modular secondary-antibody-based SERS immunoprobes for detecting membrane-associated proteins in adherent cells.

Cell membrane proteins, including receptors and ion channels, are important biomarkers and drug targets. However, most surface-enhanced Raman scattering (SERS) nanoprobes require direct conjugation of a target-specific antibody, necessitating preparation of a new probe for each target and potentially causing variabilit...