Open access
Aug 2026
Contrastive Regulatory Embeddings Attention Model for Differential Expression Prediction with Personalized Genomes: Insights and Challenges
A contrastive regulatory embedding attention model (CREAM) designed to better capture subtle sequence differences between individuals is proposed and highlighted to highlight key obstacles and suggest directions for modeling personalized gene regulation from DNA sequence.
Zhi-Rui Hu, Jason Ku, Katherine S. Pollard
· bioRxiv · 0 citations