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It is indicated that CRP and SAP have evolved distinct subcellular localization and regulatory functions, with CRP fine-tuning the NF-κB/TNFα axis and SAP promoting an IL-4-associated response.
T-cell receptor (TCR) signaling is essential for adaptive immunity in vertebrates, with the tyrosine kinases Fyn, Lck, and Zap-70 playing central roles in signal transduction. In the present study, the full cDNA sequences of Fyn, Lck, and Zap-70 from golden pompano (Trachinotus ovatus) were obtained by RT-PCR and RACE-...
A novel piscidin was identified in largemouth bass that contained an active peptide of 25 aa with an amphipathic helix possessing distinct hydrophobic and positively charged regions, and was significantly up-regulated in spleen from 6 h to 24 h post-lipopolysaccharide (LPS) stimulation.
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