Author

Zhi-Xi Hu

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Open access Oct 2026

Deciphering Vascular Smooth Muscle Cell Phenotype Switching via Integrated Single-Cell Transcriptomics and Machine Learning: CX3CR1 and COL1A1 as Novel Diagnostic Biomarkers for Atherosclerosis

Background: Atherosclerosis is a chronic inflammatory disease of the arterial wall in which immune-cell accumulation and vascular stromal remodeling jointly shape plaque progression and stability. Because bulk-tissue transcriptomes combine signals from multiple cell types, the cellular origin of candidate expression ma...

Zhi-Qi Wang, Zhen-Yu Zhao, Zhi-Xi Hu et al. · Metabolites · 0 citations

Review Open access Jul 2026

Association Between Life's Crucial 9 and the prevalence of coronary heart disease in U.S. adults: the potential role of the systemic inflammatory response index.

Higher LC9 scores were significantly associated with lower odds of prevalent self-reported CHD, while higher SIRI was associated with higher odds, which indicates that other factors may be the primary contributors to the LC9-CHD relationship.

Ji Ouyang, Jia-Yuan Song, Yingjie Wu et al. · BMC Cardiovascular Disorders · 0 citations