Small numbers of cells can determine the fate of an entire organism. For example, metastatic cancer cells seed distant organs, therapy-resistant clones repopulate tumors, and T cells infiltrate and expand in tissues with matching antigens. Visualizing the activity of such cells in living organisms requires highly sensi...
Rohit Nayak, Haein An, Trevor J. Fochtman et al.· bioRxiv· 0 citations
The first ultrasonic reporter of kinase activity (UReKA), designed to detect protein kinase A (PKA) activity by altering the ultrasound scattering of gas vesicles, is introduced, designed to detect protein kinase A activity by altering the ultrasound scattering of air-filled protein nanostructures.
Jee Won Yang, Zhi-Yang Jin, Ting-Yu Wang et al.· bioRxiv· 0 citations
Protein engineering appears to be entering a golden age, defined by a rapidly accelerating pace of progress, even as significant challenges in design, screening, and real-world application remain.
H. Ai, Frances H. Arnold, Doug Barrick et al.· Protein engineering, design...· 0 citations
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