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Zhiyuan Lu

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Open access Aug 2026

Resveratrol attenuates Cr(VI)-induced ferroptosis through SIRT3 activation in nephrocytes and in vivo.

Hexavalent chromium [Cr(VI)], a widespread environmental toxicant with mutagenic and carcinogenic potential, preferentially accumulates in the kidneys, though its nephrotoxic mechanisms remain incompletely understood. This study demonstrates that Cr(VI) induces ferroptosis, an iron-dependent regulated cell death, in ne...

Muzi Li, Pu Zhang, Zhiyuan Lu et al. · 0 citations

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