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Author

Zhizhong Xie

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Review Open access Sep 2026

Kinesins in Cancer Drug Resistance: Mechanisms, Therapeutic Targeting, and Translational Potential

Which kinesins have functional evidence supporting roles in treatment resistance, which represent potential biomarkers, and how these findings may guide the development of more selective therapies and patient stratification strategies are examined.

Ya-Yun Tan, Yi-Wei Feng, Yue-Ping Jiang et al. · 0 citations
Jul 2026

Design, Synthesis, and Evaluation of the Novel Benzimidazole Derivatives Inspired YC‐1 as HIF‐1α Inhibitor That Possess Anti‐Colon Cancer Potential

In vivo studies have shown that compound 9o can inhibit tumor growth and reduce the levels of HIF‐1α and glycolysis rate‐limiting enzyme HK2 in HCT‐116 tumor‐bearing mice, and the acute toxicity results also demonstrated the safety of compound 9o in vivo.

Qixian Yang, Jing Zhang, Meijing Liu et al. · 0 citations

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