Review
Open access
Oct 2026
Metabolites as key signaling mediators: rethinking diabetic kidney disease from a network perspective
Diabetic kidney disease (DKD) remains the leading cause of end-stage renal disease worldwide. Current diagnostic approaches rely mainly on albuminuria and eGFR, but these are insufficiently sensitive for detecting early lesions, and treatment options remain limited. Metabolites are not merely byproducts of metabolism b...
Xin Li, Xu Wang, Cheng Fang et al.
· Frontiers in Endocrinology · 0 citations