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Zhong-Hua Sun

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Open access Aug 2026

Joint associations of lipoprotein(a) and systemic inflammatory indices with FibroTouch-derived hepatic steatosis and liver stiffness in Chinese adults

Background Lipoprotein(a) [Lp(a)] is synthesized mainly in the liver, whereas blood cell-derived inflammatory indices reflect systemic immune–inflammatory status. We examined their associations with FibroTouch-assessed hepatic steatosis and liver stiffness in Chinese adults. Methods This hospital-based cross-sectional...

De-Jing Huang, Zhong-Hua Sun, Xiaolong Shen et al. · Frontiers in Immunology · 0 citations

Open access Aug 2026

Composite C-reactive protein-triglyceride-glucose adiposity indices and incident cardiovascular-liver-metabolic multimorbidity: a prospective cohort study

The C-reactive protein-triglyceride-glucose index (CTI) is a comprehensive marker that reflects inflammation and insulin resistance. Cardiovascular-liver-metabolic (CLM) diseases caused by multiple factors may be related to insulin resistance, obesity, metabolism, etc. Our aim is to explore the association between the...

Jing Chen, Zhong-Hua Sun, Jia-Jun Qiu et al. · Cardiovascular Diabetology · 0 citations

#explainable ai Open access Sep 2026

Predictive value of physical activity and walking time for dual cognitive-physical decline: a multinational cohort study using temporal deep learning and explainable AI

PA was associated with lower risk and more favorable transition patterns, although transitions to less impaired states should not be interpreted as definitive functional recovery, and Multistate Markov analyses suggested dynamic cognitive-physical state transitions.

Zhen-Hao Lin, Hao-Nan Liu, Young-Je Sim et al. · European Review of Aging and... · 0 citations

Open access Jul 2026

Association between the combined cholesterol, high-density lipoprotein, glucose index and frailty index and new-onset cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: evidence from CHARLS.

This study aimed to evaluate the association and predictive utility of the combined cholesterol, high-density lipoprotein, glucose index and frailty index (CHG-FI) for new-onset CVD, heart disease, and stroke among individuals with early-stage CKM syndrome.

Zhong-Hua Sun, Kexue Wang, Chiwei Guo et al. · Cardiovascular Diabetology · 0 citations

Jul 2026

Evidence from two large prospective cohorts: variations in remnant cholesterol inflammation index and the risk of cardiometabolic multimorbidity in middle-aged and elderly populations.

By integrating lipid and inflammatory pathways, the RCII was significantly associated with incident CMM and may enhance early risk stratification and may enhance early risk stratification.

Song Wen, Zhonghua Sun, Yanjun Song et al. · Diabetes Research and Clinic... · 0 citations