Transcriptomic Characterisation and Diagnostic Performance of S100A8, S100A9, S100B, and ENO2 (Neuron-Specific Enolase) in Pediatric Bacterial Meningitis: A Cross-Platform Re-analysis of Two Public GEO Datasets
Background: Bacterial meningitis (BM) remains a leading cause of mortality and neurological disability in children worldwide. Despite advances in antimicrobial therapy, neurological sequelae persist in up to 50% of survivors. Host-blood transcriptomic biomarkers have shown promise for early differentiation of bacterial...