Jul 2026
An integrated LC-HRMS workflow for anti-doping-relevant characterization of lapisteride metabolism in vivo and in vitro.
An integrated LC-HRMS-based workflow combining human liver microsomal incubation, CYP450 isoform verification, rat administration, multi-matrix sampling, LC-Q-TOF-MS metabolite identification, and urine/bile untargeted metabolomics is established, providing systematic evidence for lapisteride metabolism.
Zhong-Quan Li, Bing Liu, Peijie Chen
· In Analysis · 0 citations