Integrating Large-Scale Bulk and Single-Cell RNA Sequencing with Machine Learning: Unveiling the Cytokine Landscape of Glioblastoma and Constructing a Prognostic Feature Model.
INTRODUCTION Cytokines play an important role in modulating the tumor microenvironment (TME) in glioblastoma multiforme (GBM). However, little work has focused on developing a prognostic model for GBM using cytokine signatures. METHODS Herein, we combined several GBM datasets, such as GSE163120, TCGA-GBM, CGGA-693, C...