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Zhong-Hua Sun

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Open access Sep 2026

Age-specific association between remnant cholesterol and insulin resistance in women with polyendocrine metabolic ovarian syndrome

Insulin resistance (IR) is a major metabolic feature in women with polyendocrine metabolic ovarian syndrome (PMOS). Remnant cholesterol (RC), which reflects the cholesterol burden of triglyceride-rich remnant lipoproteins (TRLs), may capture lipid disturbances related to insulin-resistant dyslipidemia. Whether RC i...

Chi-Yuan Yu, Zhong-Hua Sun, Qin-Yao Wu et al. · 0 citations
Open access Oct 2026

The cholesterol, high‐density lipoprotein, and glucose index and its derivatives related to obesity and inflammation as novel metabolic markers for predicting new‐onset cardiovascular‐liver‐metabolic multimorbidity: A prospective cohort study

ABSTRACT Background Cardiovascular‐liver‐metabolic multimorbidity (CLMM), defined as the co‐occurrence of at least two of cardiovascular disease, type 2 diabetes, and metabolic dysfunction‐associated steatotic liver disease, is an increasing health burden. We evaluated the cholesterol, high‐density lipoprotein, and glu...

Zhong-Hua Sun, Aikeliyaer Ainiwaer, Ya-Meng Xu et al. · 0 citations
Open access Aug 2026

Joint associations of lipoprotein(a) and systemic inflammatory indices with FibroTouch-derived hepatic steatosis and liver stiffness in Chinese adults

Among Chinese adults, higher circulating Lp(a) was inversely associated with FibroTouch-derived hepatic steatosis and liver stiffness and combining Lp(a) with systemic inflammatory indices may provide complementary information for noninvasive cross-sectional assessment.

De-Jing Huang, Zhong-Hua Sun, Xiaolong Shen et al. · 0 citations
Open access Aug 2026

Composite C-reactive protein-triglyceride-glucose adiposity indices and incident cardiovascular-liver-metabolic multimorbidity: a prospective cohort study

The C-reactive protein-triglyceride-glucose index (CTI) is a comprehensive marker that reflects inflammation and insulin resistance. Cardiovascular-liver-metabolic (CLM) diseases caused by multiple factors may be related to insulin resistance, obesity, metabolism, etc. Our aim is to explore the association between the...

Jing Chen, Zhong-Hua Sun, Jia-Jun Qiu et al. · 1 citation
#explainable ai Open access Sep 2026

Predictive value of physical activity and walking time for dual cognitive-physical decline: a multinational cohort study using temporal deep learning and explainable AI

PA was associated with lower risk and more favorable transition patterns, although transitions to less impaired states should not be interpreted as definitive functional recovery, and Multistate Markov analyses suggested dynamic cognitive-physical state transitions.

Zhen-Hao Lin, Hao-Nan Liu, Young-Je Sim et al. · 0 citations
Open access Jul 2026

Association between the combined cholesterol, high-density lipoprotein, glucose index and frailty index and new-onset cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: evidence from CHARLS.

This study aimed to evaluate the association and predictive utility of the combined cholesterol, high-density lipoprotein, glucose index and frailty index (CHG-FI) for new-onset CVD, heart disease, and stroke among individuals with early-stage CKM syndrome.

Zhong-Hua Sun, Kexue Wang, Chiwei Guo et al. · 0 citations
Jul 2026

Evidence from two large prospective cohorts: variations in remnant cholesterol inflammation index and the risk of cardiometabolic multimorbidity in middle-aged and elderly populations.

By integrating lipid and inflammatory pathways, the RCII was significantly associated with incident CMM and may enhance early risk stratification and may enhance early risk stratification.

Song Wen, Zhonghua Sun, Yanjun Song et al. · 0 citations

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